Areas of Expertise: AIDS, arthritis, cancer, proteases in emphysema and parasites, drug design, clinical diagnostics.
Invented DATE Analysis.pdf, the first quantitative theory of biological change. DATE comes from Differentiation, Adaptation, Transformation, Evolution. It is an extension of my theoretical work on the aneuploidy theory of cancer.
Participated as a member of The Presidential AIDS Advisory Panel of South Africa initiated by President Thabo Mbeki.
Synthesized the first peptidyl-fluoromethanes. These molecules are biologically stable inhibitors of cysteine proteases used around the world in the development of therapies for the tissue-destroying diseases of arthritis, cancer, and parasites, among others.
Founded several biotech companies.